Research by M. Carlessi, B. Franchetti, A. Venco, F. Pietrolucci, S. Negri, C. Ramos, L. Avesani, and F. Guzzo analyses growing medicinal plant Artemisia in vertical farming under different LED light conditions.
Malaria is one of the most serious health problems in developing countries. According to the WHO, in 2020, about half of the world's population was at risk of Malaria, with an estimated 241 million cases worldwide. One of the most effective and inexpensive antimalarial therapies is the administration of artemisinin.
This bioactive compound is extracted from the leaves of the medical plant Artemisia annua L. Low concentration of artemisinin within the plant and the fluctuating costs due to its inconsistent availability still represent a major bottleneck for the large-scale, sustainable production of artemisinin.
"In this work, we report indoor vertical farming as a promising system for the sustainable production of the Artemisia plant. Indoor vertical farming consists in growing plants in a closed and fully controllable environment, not conditioned by external environmental conditions. Such growing conditions guarantee a high-quality, consistent production with a high concentration of the desired active molecules.
Using this farming practice, it is possible to engineer the growth of medicinal plants, which will express their maximum potential, allowing them to obtain a product of high therapeutic value. Several studies have demonstrated how the artemisinin content varies during plant development and how the accumulation of this molecule can be affected by photoperiod and light intensity.
Our research focused on the improvement of Artemisia annua L. growth and on methods for increasing the artemisinin content by varying the LED light properties. Specific indoor vertical farming procedures were established for the optimization of Artemisia growth. Leaves samples were harvested at two different time points during the plantRSQUOs growth. Artemisinin content was analyzed using the UPLC-MS/MS method, and a significant amount of this compound, in the range of 0.6-1% (%DW), was observed in all the samples.
The results show how indoor vertical farming has the potential for efficient and sustainable production of Artemisia plants."
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Carlessi, M., Franchetti, B., Venco, A., Pietrolucci, F., Negri, S., Ramos, C., Avesani, L. and Guzzo, F. (2023). Growing medicinal plant Artemisia in vertical farming under different LED light conditions. Acta Hortic. 1358, 295-302 DOI: 10.17660/ActaHortic.2023.1358.38